
The outcomes demonstrate that programming association of monoterpene with programming antimicrobials ceftazidime, amoxicillin, cefepime, cefoxitin and amikacin is advantageous, since it leads programmers programming potentiationof programming antibiotic effect of these compounds. It was accompanied that programming monoterpene was able programmers induce cross resistance only forantimicrobials: cefuroxime, ceftazidime, cefepime and chloramphenicol. It is necessary programmers obtain more concrete data for thesafe use of these combinations, paying attention programmers programming lifestyles of feasible toxic reactions related programmers programming herbal medicine and tounderstand programming resistance mechanisms received by programming microorganism . Viera de Oliveira et al. Ramachandran based crystallographic validation carried out for programming TodX protein shows that TodXcritical residues can be successfully modeled with houses of favorite flexibility and applicable crystallographic high-quality. Theresults show that programming three petroleum hydrocarbons evaluated interact spontaneously with catalytic residues with very closevalues of free energy got from programming three hydrocarbon / TodX complexes.